RXR Retinol Anti-Aging Serum

Estimated 90 day Supply

  • Cellular Renewal Anti-Aging
  • Brightening
(60)
Size
Description:

1% active retinol in a solid lipid encapsulation system formulated for nightly use on all skin types, including retinol-sensitive skin. A multi-active, anti-aging blend promotes cellular turnover to visibly reduce fine lines, wrinkles, uneven tone, and blemishes.

Key Ingredients:

Retinol (Vitamin A)Promotes cellular turnover and stimulates collagen synthesis to diminish the appearance of fine lines and wrinkles.

CoQ10 (Coenzyme Q10)A powerful antioxidant that protects skin from environmental stress and supports DNA defense.

Nano Liposomal Resveratrol- Potent antioxidant that neutralizes oxidative stress and supports cellular DNA repair overnight

Tripeptide-5 Signals the skin to produce its own collagen and elastin to restore firmness and visibly reduce deep lines over time.

Benefits:
  • Promotes cellular turnover and stimulates collagen synthesis to smooth fine lines and improve texture
  • Gentler delivery system makes it suitable for nightly use, including sensitive skin types
  • Visibly reduces hyperpigmentation and brown spots for a visibly brighter complexion
  • Targets pigmentation, texture, and fine lines simultaneously

*Cruelty-free formula made with clean ingredients. Free of parabens, fragrance, and phthalates.*

I’ve tried many medical grade retinol serums and this one by far is the best… I’ve never had redness, flaking, or dry skin… My skin feels smooth and overall has improved tone and texture.

This is the only retinol I’ll ever use on my face… I never have any irritation and I have sensitive skin. I love it!

I love this product… reduced fine lines… smooth skin texture… I’ve repurchased at least 6 times… there aren’t a lot of products I repurchase!

From Dr. Kappel

How to use this product in your routine.

  1. 1.

    Prep

    Start with freshly cleansed and dry skin.

  2. 2.

    Renew

    Apply a thin, even layer of RXR Retinol to the face during your evening routine. Avoid the periorbital eye area.

  3. 3.

    Adjust

    Begin using 3 nights per week and gradually increase frequency to nightly as tolerated

  4. 4.

    Hydrate

    Follow or sandwich with NMF Hydrator Barrier Repair or NMF Intense Barrier Cream to support hydration and barrier recovery.

Why MDAiRE

The science difference

The Problem

Why most serums don't deliver

  • Your skin seemed to be losing resilience with age. It stops bouncing back, and products absorb differently than they once did.
  • Retinol delivers results, but redness, peeling, and irritation make it impossible to stay consistent.
  • Layering multiple actives at night often means compromising absorption. Some ingredients compete, others cancel each other out. It's hard to keep straight.

The MDAiRE™ Solution

Formulated to actually work

  • Declining collagen, elastin, and cellular turnover are the cause. Tripeptide-5 rebuilds structure, Retinol accelerates renewal, and CoQ10 protects against the oxidative stress that drives the breakdown.
  • Our solid lipid encapsulation releases retinol gradually throughout the night, dramatically reducing irritation while keeping efficacy fully intact.
  • RXR Retinol is formulated as a complete system formulation so every active is already optimized to work together. No extensive layering, no guesswork, and no conflict.

Reviews

What our customers say

4.8
Rated 4.8 out of 5 stars
Based on 60 reviews
Total 5 star reviews: 55 Total 4 star reviews: 2 Total 3 star reviews: 1 Total 2 star reviews: 1 Total 1 star reviews: 1
95%would recommend this product
I saw and/or Felt Results in my SkinRated 4.6 on a scale of 1 to 5
60 reviews
  • FB
    Francesca B.
    Verified Buyer
    I recommend this product
    How old are you? Over 65
    Product Standouts Texture, Gentle, Hydrating, Great Ingredients
    If you saw results, what were they? Clear Skin, Brighter Skin, Fewer Blemishes, Reduced Irritation
    Would you purchase this product again? Yes!
    Rated 5 out of 5 stars
    1 month ago
    Results you can see - gentle

    Love this Retinol! Diff than anything on the market! Gentle yet very effective- see results each am after using the night before/ each day. Have learned how to layer this for night and day usage- easy as can be!! MDAIRE PRODUCTS WORK!!! My skin is clear, smooth, lovely ivory color not red and irritated as it used to be… I will never switch from the program!!

    I saw and/or Felt Results in my SkinRated 5.0 on a scale of 1 to 5
  • DM
    Deborah M.
    Verified Buyer
    I recommend this product
    How old are you? Over 65
    Product Standouts Dramatic Results, Absorption, Packaging, Great Ingredients
    If you saw results, what were they? Reduced Fine Lines, Smoother Texture
    Would you purchase this product again? Yes!
    Rated 5 out of 5 stars
    2 months ago
    RXR retinol anti aging serum

    I was a little skeptical about trying this, but of my glad I did. The serum goes on very light and not greasy. I’ve been using it for about a week and I’m starting to see some of my fine lines fade. I will continue to buy.

    I saw and/or Felt Results in my SkinRated 5.0 on a scale of 1 to 5
  • CR
    Carolyn R.
    Verified Buyer
    I recommend this product
    How old are you? 45-54
    If you saw results, what were they? Brighter Skin, Smoother Texture , Smaller Pores, Clear Skin
    Would you purchase this product again? Yes!
    Rated 5 out of 5 stars
    2 months ago
    Fantastic all in one

    This retinol cream is so easy to use and because it’s gentle I can use it nightly without any of the typical issues with Reina. I am definitely seeing a difference in my skin and it absolutely glows. Thank you so much.

    I saw and/or Felt Results in my SkinRated 5.0 on a scale of 1 to 5

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